By breaking down parts of the brain that are usually separate, drugs like LSD return us to a childlike state — and that effect on well-being could last long after the drugs’ effects have worn off.
LSD makes the brain more “complete”, scientists have claimed in land breaking new study.
The drug breaks down the parts of the brain that usually separate different functions, like vision and movement, creating a more “integrated or unified brain”, the researchers claim. They also found that people who are having drug-induced hallucinations “see” with various other parts of their brain, not just the visual cortex that is active in normal vision.
Those effects might account for the religious feelings that people often report after having taken the drug, the researchers say — a claim that if true could answer some of the deepest questions of drug culture. And those same effects on a person’s well-being might carry on long after the effects of the drug has worn off.
“Normally our brain consists of independent networks that perform separate specialised functions, such as vision, movement and hearing – as well as more complex things like attention,”
“However, under LSD the separateness of these networks breaks down and instead you see a more integrated or unified brain.
“Our results suggest that this effect underlies the profound altered state of consciousness that people often describe during an LSD experience. It is also related to what people sometimes call ‘ego-dissolution’, which means the normal sense of self is broken down and replaced by a sense of reconnection with themselves, others and the natural world.
“This experience is sometimes framed in a religious or spiritual way – and seems to be associated with improvements in well-being after the drug’s effects have subsided.”
By breaking down the constraints that usually keep parts of the brain separate, psychedelic drugs return their users back to a state that is more like childhood, the researchers said in work published in the Proceedings of the National Academy of Sciences.
“Our brains become more constrained and compartmentalised as we develop from infancy into adulthood, and we may become more focused and rigid in our thinking as we mature,” said Dr Carhart-Harris. “In many ways, the brain in the LSD state resembles the state our brains were in when we were infants: free and unconstrained.
“This also makes sense when we consider the hyper-emotional and imaginative nature of an infant’s mind.”
“We are finally unveiling the brain mechanisms underlying the potential of LSD, not only to heal, but also to deepen our understanding of consciousness itself.”
And those effects could be even further encouraged with the use of music, according to results from the same study, which was published in the journal European Neuropsychopharmacology. Listening to music while under the influence of the drug led the visual cortex to receive information from the part of the brain that usually deals with mental images and memory — and the more it did so, the more people reported seeing complex visions including those from earlier in their lives.
Those discoveries help answer questions that have been asked for decades about how exactly LSD works, and what it does to the brain, the researchers said.